Semaglutide Calculator & Guide

📋 Semaglutide Titration Schedule

Semaglutide requires gradual dose increases to minimize side effects:

🧬 What is Semaglutide?

Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist. It mimics a hormone naturally produced in your gut after eating.

How It Works

• Slows gastric emptying — Food stays in your stomach longer, increasing fullness
• Reduces appetite centrally — Acts on brain receptors that control hunger
• Improves insulin sensitivity — Originally developed for type 2 diabetes
• Reduces "food noise" — Many report less obsessive thoughts about food

Brand Names

• Ozempic — FDA-approved for type 2 diabetes
• Wegovy — FDA-approved for weight loss (same drug, higher dose range)
• Rybelsus — Oral tablet form

⚡ Side Effects & Management

Common Side Effects

• Nausea — Most common, especially early. Usually improves over weeks.
• Constipation or diarrhea — GI system adjusting
• Decreased appetite — The intended effect, but can be extreme initially
• Fatigue — Often related to reduced calorie intake

Managing Nausea

• Titrate slowly — don't skip dose steps
• Eat smaller, more frequent meals
• Avoid fatty, greasy, or heavy foods
• Ginger tea or ginger supplements
• Stay hydrated

💾 Storage Guidelines

Unreconstituted (Powder)

• Freezer (-20°C): Up to 2 years
• Refrigerator (2-8°C): 6-12 months
• Keep away from light

Reconstituted

• Refrigerator only: 4-6 weeks
• Never freeze after reconstitution
• Use bacteriostatic water (not sterile water)
• Always use sterile technique when drawing doses

🛒 Supplies You'll Need

Essential supplies for reconstitution and injection:

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